PJB-2023-182
Ehnopharmacological and phytochemical evaluations of desert plant Calligonum polygonoides - Polygonaceae
Fatima Sadiq, Mirza Imran Shahzad, Sarah Tariq, Marcello Locatelli, Angela Tartaglia, Ghulam Mustafa Kalyar, Hina Ashraf and Irfan Saeed
Abstract
The use of medicinal plants for the treatment of various ailments has significantly expanded due to the high cost and adverse effects of allopathic medicines. In the current investigation stem, root, and flower of C. polygonoides were used to make Aqueous (Aq), MtOH, EtOAc, EtOH, and n-hexane extracts. Qualitative phytochemical analysis has revealed the presence of carbohydrates, proteins, glycosides, and other phytochemicals. According to HPLC-PDA analysis results different phenolic compounds were present in significant quantities. In antibacterial activity, EtOAc extracts of stem and root whereas EtOH extract of the flower was most effective though all the other extracts were positive in varying order. In the antibiofilm assay, EtOH extract of stem and root whereas multiple extracts of the flower have shown high antibiofilm potential. Antioxidant potentials observed by DPPH assay revealed that MtOH extract of the stem, EtOH extract of roots, and EtOH extract of flowers showed max scavenging potential. Similarly, in FRAP assay the EtOAc extract of the stem, MtOH extract of root, and n-hex extract of the flower have shown the highest antioxidant potentials. In case of α-glucosidase inhibition assay, Aq extracts of stem and root have shown max activity, though, all extracts of flowers have shown excellent inhibition potential. According to antiviral activity, Aq extracts of different parts were most active against AIVH9N2 whereas, in the case of IBV different extracts were active in varying order. It can be positively stated that C. polygonoides possesses great pharmacological importance and is a rich source of multiple compounds with biological activity.
To Cite this article:
Sadiq, F., M.I. Shahzad, S. Tariq, M. Locatelli, A. Tartaglia, G.M. Kalyar, H. Ashraf and I. Saeed. 2025. Ehnopharmacological and phytochemical evaluations of desert plant Calligonum polygonoides – Polygonaceae. Pak. J. Bot., 57(1): DOI: http://dx.doi.org/10.30848/PJB2025-1(25)
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